137 Hypogammaglobulinemia in a Boy: Consider Also X-linked Lymphoproliferative Disease
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چکیده
immunohistochemistry.Human turbinates were obtained after turbinectomy from 6 patients with nasal obstruction refractory to medical therapy. Total RNA was isolated from human nasal mucosa, and CysLT2 receptor mRNA was detected in these tissues by using reverse transcriptase-PCR analysis. To identify the cells expressing CysLT2 receptor protein, double immunostaining was performed using anti-CysLT2 receptor antibody and anti-CD31 (endothelial cell) antibody. Results: Reverse transcriptase-PCR analysis of total nasal RNA demonstrated the expression of CysLT2 receptor mRNA. The immunohistochemical studies revealed that anti-CysLT2 receptor antibody mainly labeled blood vessels. Conclusions: The results suggest a primary role for CysLT2 receptor as the vascular responses in upper respiratory tract.
منابع مشابه
Immune Globulin Therapy
Intravenous immunoglobulin (IVIg) therapy may be considered medically necessary for the following indications. Immunodeficiency States—patients with Primary Immunodeficiencies, including o Congenital agammaglobulinemia o Hypogammaglobulinemia o Common variable immunodeficiency o Severe combined immunodeficiency (SCID) o Wiskott-Aldrich syndrome o X-linked agammaglobulinemia (Bruton agammaglob...
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